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Navigating MFP Effectuation Under the IRA

Equip Pharma Teams to Execute MFP Compliance, Accelerate Payments, and Optimize Revenue Under the IRA

A practical guide for pharmaceutical manufacturers to master compliance, streamline payment operations, and optimize revenue strategy under the Inflation Reduction Act’s Maximum Fair Price (MFP) mandate.

MFP_Effectuation_eBook_2025_front_page

Unlock Compliance and Revenue Strategy in the New Era of Drug Pricing

The Inflation Reduction Act (IRA) introduces transformative changes to Medicare drug pricing, with the Maximum Fair Price (MFP) mandate at the forefront. For pharmaceutical manufacturers, MFP effectuation brings new regulatory, operational, and financial challenges—from accelerated payment cycles to complex forecasting and compliance requirements. This eBook delivers a clear, actionable roadmap to help manufacturers navigate MFP implementation, avoid costly pitfalls, and seize strategic opportunities in a rapidly evolving landscape.

Key takeaways

  • Understand the fundamentals of MFP effectuation and its impact on pricing, rebates, and compliance.
  • Learn how to adapt payment operations to meet the 14-day MFP refund mandate.
  • Discover strategies for integrating MFP into gross-to-net (GTN) models and government pricing systems.
  • Pressure-test your organization’s readiness with a comprehensive checklist for policy, planning, and payment processing.
  • Explore Model N’s solutions for chargeback-style processing, ERP integration, and real-time GTN modeling.
  • Prepare for future regulatory shifts, including potential Most Favored Nation (MFN) pricing mandates.
ebook
ebook
ebook
Unlock the value of your revenue management data
This eBook helps business users drive improvements across a range of critical business functions, including pricing decisions, rebate accuracy, and deal negotiations. VIEW ebook
Press Release
webinar
webinar
webinar
Navigating IRA Compliance: MFP Regulations and the 340B Rebate Model
VIEW webinar
whitepaper
whitepaper
whitepaper
Best Practices for Complying with 340B
Read this white paper to learn how you can improve the chargeback process, generate an audit trail, and ensure correct 340B pricing. VIEW whitepaper